Her performance alone in Robert Zemeckis comedy from 1978, I Wanna Hold Your Hand, is living proof of the comic gift that she possessed. Other comedies came her way, like 1941, Used Cars and Back to the Future, but the roles were smaller and she just never caught on with the movie-going public.
Part Gilda Radner, part Vivian Vance, Wendie Jo Sperber should have been the female comedy sensation of the 1980's, but like so many talented performers before and after her, it just wasn't in the cards.
In 2005, after a long and courageous battle with Cancer, Wendie Jo Sperber passed away at the young age of 47. Her TV shows and movies are still around and are worth a look, but if you can, check out her work in I Wanna Hold Your Hand. I think you'll see for yourself what I am talking about.